Buy Alloxan monohydrate (CAS ), a water soluble pyrimidine derivative & glucose analog. Join researchers using high quality Alloxan monohydrate. Alloxan monohydrate | C4H4N2O5 | CID – structure, chemical names, physical and chemical properties, classification, patents, literature, biological. Alloxan monohydrate (Sigma Aldrich, St. Louis, MO, USA; stored at 4°C) was dissolved in normal saline at room temperature and was injected by intraperitoneal.

Author: Vonris Nigar
Country: Martinique
Language: English (Spanish)
Genre: Software
Published (Last): 25 December 2012
Pages: 158
PDF File Size: 8.3 Mb
ePub File Size: 7.48 Mb
ISBN: 627-3-19134-126-8
Downloads: 71814
Price: Free* [*Free Regsitration Required]
Uploader: Arakree

Is alloxan kit available in your shop. How long would shipping usually take to the Philippines? These results indicate that the susceptibility to diabetogenic and toxic effects of alloxan differs among animals of the same species. In diabetic rats and rabbits, random fluctuations in FBG with blood sugar returning to the allodan range at various time periods during the study duration was observed.

This product has been referenced in: Santa Cruz Biotechnology, Inc. Send me a copy of this email. A cytotoxic compound that causes oxidative base damage to nuclear DNA. Healthy adult albino rats g and rabbits 1.

Rated 4 out of 5 by adebman from Excellent Reagent, worked well Good reagent well packaged. Submit a review Submit a question.

Your account has been deactivated. It is classified as a derivative of pyrimidine. Author information Copyright and License information Disclaimer.

Monika Misra and Umme Aiman. Variations of susceptibility to alloxan induced diabetes in the rabbit. Create an account quickly and easily with your preferred social network account.

Alloxan monohydrate (ab143569)

Induces diabetes mellitus in vivo. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for mknohydrate least 1 hour. Retrieved from ” https: Need more advice on solubility, usage and handling?


Certificate of Analysis Catalog Number sc Don’t have an account? Levi considers the droppings of pythons as a source for uric acid for making alloxan, but he is turned down by the director of the Turin zoo because the zoo already has lucrative contracts with pharmaceutical companies, so he is obliged to use chickens as his source of uric acid. The high degree of resistance to alloxan in rats suggests genetic differences in the constitutive ability to dissipate reactive oxygen species monohydrat for diabetogenic effect alloxqn alloxan.

For the best experience on the Abcam website please upgrade to a modern browser such as Google Chrome. You can save favorites, save cart, check order status and speed through checkout with saved addresses, payment methods and more.

Alloxan, in the presence of intracellular thiolsgenerates reactive oxygen species ROS in a cyclic reaction with its reduction product, dialuric acid. The rats that were nondiabetic after initial dose of alloxan showed no impairments in oral glucose tolerance test and remained resistant to two subsequent doses of alloxan injected at 1 week interval. They also exhibit a variety of biological activities. Alloxan monohydrate Sigma Aldrich, St. The beta cell toxic action of alloxan is initiated by free radicals formed in this redox reaction.

These fluctuations had no discernible pattern.


Our Cookie Policy explains how you can opt-out of the cookies we use. Gaspare Brugnatelli “Sopra i cangiamenti che avvengono nell’ ossiurico ac. All trademarks are the property of their respective owners.


Anomalies in alloxan-induced diabetic model: This page was last edited on 28 Januaryat Because it selectively kills the insulin -producing beta-cells found in the pancreas, alloxan is used to induce diabetes in monohyrrate animals.

Not Intended for Diagnostic or Therapeutic Use. We, therefore, agree with the viewpoint of Jain DK et al,oxan. Please use the links above to contact us or submit feedback about this product. Indian J Exp Biol Alloxam causes an insulin-dependent diabetes mellitus called “alloxan diabetes” in these animals, with characteristics similar to type 1 diabetes in humans.

Antidepressant-like effects of Brassica juncea L. In addition, alloxan has a high affinity to SH-containing cellular compounds and, as a result, reduces glutathione content.

Alloxan monohydrate | CAS | SCBT – Santa Cruz Biotechnology

Creating an account with us makes your shopping experience much easier and faster. In other projects Wikimedia Commons. Thereafter, FBG was recorded at days 3, 7, 14, 21, 28, and 35 to determine fluctuations in FBG or autoreversal of diabetes. Get resources and offers direct to your inbox Sign up.

Effect of rate of injection of monohydrxte on development of diabetes in rabbits. Sign Up for Santa Cruz Biotechnology news and announcements.

Please let us know so that we can cite the reference in this alloxan.

Call us Toll Free at